BOSTON -- Vernon Ingram, the Massac...

BOSTON -- Vernon Ingram, the Massachusetts Institute of Technology professor whose landmark discovery upon the cause of sickle- small cavity anemia made him a pioneer in the field of molecular biology, has died. He was 82

Mr Ingram died Aug. 17 after a fall, according to the MIT recents office.

In 1957 he discovered that a single amino acid substitution is responsible for the molecular abnormality that leads to sickle-cell anemia.

In new years, Mr. Ingram, of Cambridge, had focused forward neuroscience, especially Alzheimer's disease.

Born in Breslau, Germany, he studied at Birkbeck society at the University of London, where he earned his bachelor's measure in chemistry in 1945 and doctorate in organic chemistry in 1949

In 1952 he studied protein chemistry at the Cavendish Laboratory of Cambridge University. A not many years later, while studying the genetics of hemoglobin, the indivisible particle that carries oxygen in the vital fluid Mr. Ingram discovered that the misshapen hemoglobin ultimate particle s that characterize sickle-cell anemia are caused by the agency of a single mutation.

He joined the MIT faculty in 1958

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